Research never stops

Publications 2014

Title Source

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014

Bodkin MJ, Heifetz A., Law RJ, Singh S. et al.

PMC US National Library of Medicine National Institutes of Health, 2015


Tropomyosin receptor kinase inhibitors: a patent update 2009 – 2013

McCarthy, C., Walker, E.

Expert Opinion on Therapeutic Patents, 2014, 24, 7, 731–744

Evaluation of Host/Guest Binding Thermodynamics of Model Cavities with Grid Cell Theory

Law, R.J., Mazanetz, M.P., Southey, M.W.Y. et al.

Journal of Chemical Theory and Computation, 2014, 10 (9), pp 4055–4068

Design, synthesis and structure–activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK)

Trani, G., Barker, J. J., Bromidge, S. M. et al.

Bioorganic & Medicinal Chemistry Letters, 2014, 24, 5818-5823

Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

Šišková, Z., Justus, D., von der Kammer, H. et al.

Neuron, 2014

High-Throughput Screening

Böcker, A., Schaertl, S., Hess, S.

Ion Channel Drug Discovery, 2014, 16-41

Identification of Significant Features by the Global Mean Rank

Klammer, M., Dybowski, J.N., Hoffmann, D., Schaab, C.

PLoS One 2014, 9 (8), e104504

Global phosphoproteome analysis of human bone marrow reveals predictive phosphorylation markers for the treatment of acute myeloid leukemia with quizartinib

Schaab, C., Oppermann, F.S., Klammer, M. et al.

Leukemia, 2014, 28, 716–719

Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins

Macdonald, D., Tessari, M., Herrmann, F. et al

Plos One, 2014, 9 (5), 


Investigation of the Flexibility of Protein Kinases Implicated in the Pathology of Alzheimer’s Disease

Mazanetz, M.P., Laughton, C.A., Fischer, P.M.

Molecules 2014, 19(7), 9134-9159

Evaluation of Host/Guest Binding Thermodynamics of Model Cavities with Grid Cell Theory

Michel J; Henchman RH; Mazanetz MP et al 

J. Chem. Theory Comput., Accepted Manuscript